DDB1
DNA Damage Binding Protein-1 (DDB1) is a protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. The ubiquitin–proteasome system is a significant pathway that precisely governs protein stability. Among the Cullin-RING Ligase (CRL) family, a typical CRL4 ligase is composed of a scaffold Cullin (CUL4A or CUL4B) protein, a linker protein-DDB1, a substrate recognition adaptor (DCAF), and a ring protein with intrinsic E3 activity (RBX1 or RBX2).
-
DDB1 Related Products (1)
Related Products (1)
-
DDB1 ligand-2
0 ImagesCat. No.: HY-175890DDB1 ligand-2 is an E3 ligase ligand. DDB1 ligand-2 can be coupled with BRD4 ligand JQ-1 carboxylic acid (HY-78695) via the linker NH2-C5-NH-Boc (HY-W004710) to form PROTAC MM-02-08 (HY-161167).
